Provinase®

Provinase® is our Flagship Product, highly active recombinant endonuclease designed to digest all forms of DNA and RNA, reducing viscosity and improving downstream host cell DNA removal efficiency

Provinase® is a robust, animal-origin-free endonuclease designed specifically to address challenges in modern bioprocessing. It efficiently digests single-stranded, double-stranded, linear and circular DNA and RNA, significantly reducing sample viscosity. It performs reliably across a wide range of operational pH and temperature parameters, delivering optimal removal of host-cell nucleic acid impurities in complex bioproduction workflows.