Provinase™ is a genetically engineered endonuclease enzyme from Serratia marcescens expressed in E. coli. It is a dimer of 30 kDa subunit with two disulphide bonds and it attacks and digests all forms of DNA and RNA. Provinase™ endonuclease acts only on nucleic acids and do not interact with proteins and other biomolecules.

Provinase™ is GMP manufactured in a certified facility with animal component free certified raw materials.

Provinase™ used in nucleic acid removal applications in manufacturing of biotechnology products such as:

  • Viruses and virus like particles in vaccines.
  • Viral vectors and lentivirus for gene/cell therapies and oncolytic vaccines.
  • Viscosity reduction in cell lysates.

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Provis Biolabs pvt Ltd, is a Hyderabad, India based Biotechnology Company founded in the year 2019 to develop, Manufacture and market complex Biotechnology products through sustainable means.

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